BDBM50618043 CHEMBL5424034

SMILES CCc1ncc(-c2cc(C)no2)c(n1)C1CCN(CCN2CCOCC2)CC1

InChI Key InChIKey=XYJJFGCFMUCSKK-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50618043   

TargetSigma intracellular receptor 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50618043(CHEMBL5424034)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50618043(CHEMBL5424034)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor transfected in HEK293 cell membranes assessed as inhibition constant incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Welab Barcelona

Curated by ChEMBL
LigandPNGBDBM50618043(CHEMBL5424034)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells at holding potential of -80 mV measured for 15 seconds by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed