BDBM50618122 CHEMBL5413269

SMILES [H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](CCCCCC(=O)NO)NC2=O)[C@@H](C)CC

InChI Key InChIKey=AYXFWPSPCQNMLC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50618122   

TargetHistone deacetylase 3(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to HDAC3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to HDAC1 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to HDAC2 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to HDAC3 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  18nMAssay Description:Binding affinity to human HDAC11 assessed as inhibition constant (ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50618122(CHEMBL5413269)
Affinity DataKi:  23nMAssay Description:Binding affinity to recombinant human HDAC6 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured after 60 mins assessed as inhibition constant (ki,1) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed