BDBM50618124 CHEMBL5416731

SMILES CN(C)c1ccc(cc1)C(=O)N(CC(=O)NC(C)(C)C)Cc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1ccncc1

InChI Key InChIKey=BGRYBJIQYBKCOQ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50618124   

TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 21nMAssay Description:Inhibition of human HDAC1 using Z-Lys(Ac)-AMC as substrate measured after 120 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 28nMAssay Description:Inhibition of human HDAC1 using Z-Lys(Ac)-AMC as substrate measured after 60 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 35nMAssay Description:Inhibition of human HDAC1 using Z-Lys(Ac)-AMC as substrate measured after 30 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 49nMAssay Description:Inhibition of human HDAC1 using Z-Lys(Ac)-AMC as substrate measured after 15 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC1 using Z-Lys(Ac)-AMC as substrate measured after 5 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 78nMAssay Description:Inhibition of human HDAC2 using Z-Lys(Ac)-AMC as substrate measured after 120 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 84nMAssay Description:Inhibition of human HDAC2 using Z-Lys(Ac)-AMC as substrate measured after 60 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 106nMAssay Description:Inhibition of human HDAC2 using Z-Lys(Ac)-AMC as substrate measured after 15 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 109nMAssay Description:Inhibition of human HDAC2 using Z-Lys(Ac)-AMC as substrate measured after 30 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618124BDBM50618124(CHEMBL5416731)
Affinity DataIC50: 117nMAssay Description:Inhibition of human HDAC2 using Z-Lys(Ac)-AMC as substrate measured after 5 min by ascent Fluoroskan microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed