BDBM50618448 CHEMBL5428800

SMILES COc1ccc2c(c1)oc(c\c2=N/O)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=KLDZWUKEYNHSOV-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50618448   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50618448(CHEMBL5428800)
Affinity DataKd:  0.110nMAssay Description:Binding affinity to human recombinant IDO1 assessed as dissociation constant measured for 60 sec by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50618448(CHEMBL5428800)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant IDO1 measured after 60 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Guilin Medical University

Curated by ChEMBL
LigandPNGBDBM50618448(CHEMBL5428800)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of IDO1 in IFN-gamma treated human HeLa cells incubated for 48 hrs by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed