BDBM50618612 CHEMBL5423817

SMILES CNc1ncc2cc(-c3cc(Cl)ccc3Br)c(=O)n(CCCCN)c2n1

InChI Key InChIKey=LHZJHTRTELKUDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50618612   

TargetSerine/threonine-protein kinase SIK1(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618612(CHEMBL5423817)
Affinity DataIC50: 228nMAssay Description:Inhibition of full length NanoLuc fused SIK1 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618612(CHEMBL5423817)
Affinity DataIC50: 290nMAssay Description:Inhibition of full length NanoLuc fused SIK3 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50618612(CHEMBL5423817)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length NanoLuc fused SIK2 (unknown origin) transfected in HEK293T cells using NanoBRET NanoGlo substrate incubated for 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed