BDBM50618685 CHEMBL5422596

SMILES CCc1c(c2ccc(cc2o1)O)C(=O)c3cc(c(c(c3)I)O)I

InChI Key InChIKey=YOSYHCQGAMQBMM-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50618685   

TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50618685(CHEMBL5422596)
Affinity DataKd:  410nMAssay Description:Binding affinity to thyroxin binding site of TTR V30M mutant (unknown origin) expressed in Escherichia coli assessed as quenching of intrinsic trypto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50618685(CHEMBL5422596)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of acid mediated TTR V30M mutant aggregation (unknown origin) expressed in Escherichia coli preincubated for 30 mins followed by acetic bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)