BDBM50618724 CHEMBL5426036

SMILES COc1ccc(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1OCCOCCn1ccnc1[N+]([O-])=O

InChI Key InChIKey=KRHJQHMWPVTYCU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50618724   

TargetTyrosine-protein kinase JAK2(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 31nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 43nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 107nMAssay Description:Inhibition of ROS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 108nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 177nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 227nMAssay Description:Inhibition of FLT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Hangzhou City University

Curated by ChEMBL
LigandPNGBDBM50618724(CHEMBL5426036)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed