BDBM50618946 CHEMBL5417927

SMILES CN1CCC(CC1)c1ccc(Nc2ncc3ccc(cc3n2)-c2cnc3CCNCc3c2)cc1

InChI Key InChIKey=DANGUZMANKPIJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50618946   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandPNGBDBM50618946(CHEMBL5417927)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of full-length human GST-tagged HPK1 expressed in baculovirus infected Sf21 insect cells using MBP and ATP as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed