BDBM50618953 CHEMBL5431039

SMILES CN1CCC(c2ccc(Nc3ncc4ccc(-c5cnc[nH]5)cc4n3)cc2)CC1

InChI Key InChIKey=CGHXYQRJBUGENS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50618953   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Emd Serono Research & Development Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50618953BDBM50618953(CHEMBL5431039)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full-length human GST-tagged HPK1 expressed in baculovirus infected Sf21 insect cells using MBP and ATP as substrate preincubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed