BDBM50619171 CHEMBL5424840

SMILES Nc1nc(NC2=NC(=CC(O2)c2ccccc2Cl)c2ccccc2)nc(n1)N1CCOCC1

InChI Key InChIKey=KAMHSKDHTIWRAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619171   

TargetDipeptidyl peptidase 4(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619171(CHEMBL5424840)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant DPP-4 using H-GlyPro-AMC as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619171(CHEMBL5424840)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal GST/His-tagged human recombinant DPP-8 (1 to 898 residues) expressed in Sf9 insect cells using Ala-Pro-AMC dipeptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619171(CHEMBL5424840)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant DPP-9 short form (1 to 863 residues) expressed in Sf9 cells using Ala-Pro-AMC dipeptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed