BDBM50619186 CHEMBL5437226

SMILES CCS(=O)(=O)Oc1ccc(CN(Cc2ccc(F)cc2)C(=O)CCl)cc1

InChI Key InChIKey=KBRXYMSMHKLIGI-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50619186   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTranscriptional coactivator YAP1(Homo sapiens)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 residues)(unkno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataKi:  4.58E+4nMAssay Description:Covalent inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Indiana University School of Medicine 635 Barnhill Drive

Curated by ChEMBL
LigandPNGBDBM50619186(CHEMBL5437226)
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of GST-tagged TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells/FAM-labelled YAP1 (60 to 99 resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed