BDBM50619381 CHEMBL5403228

SMILES CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ncccn4)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1

InChI Key

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619381   

TargetHistamine H1 receptor(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619381(CHEMBL5403228)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]pyrilamine from Sprague-Dawley rat H1 receptor assessed as inhibition constant measured after 30 mins by competitive binding assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619381(CHEMBL5403228)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at Sprague-Dawley rat hippocampal membrane 5-HT1A receptor assessed as stimulation of [35S]GTPgammaS binding measured after 90 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Medical University of Warsaw

Curated by ChEMBL
LigandPNGBDBM50619381(CHEMBL5403228)
Affinity DataIC50: 2.26E+4nMAssay Description:Antagonist activity at Sprague-Dawley rat striatum membrane D2 receptor assessed as inhibition of dopamine stimulated [35S]GTPgammaS binding measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed