BDBM50619386 CHEMBL5424516

SMILES COc1cc2ncnc(NCc3ccc(NC(=O)C(N4Cc5ccccc5C4=O)c4ccccc4)cc3)c2cc1OCCCN1CCOCC1

InChI Key InChIKey=NABZOYHCDFBNPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50619386   

TargetEpidermal growth factor receptor(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50619386(CHEMBL5424516)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50619386(CHEMBL5424516)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant in human NCI-H1975 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed