BDBM50619536 CHEMBL5429318

SMILES [H][C@]1(CC[C@H]1N)C(=O)N1CCN2c3nc(OC[C@@H]4CCCN4C)nc4cc(c(Cl)c(OC[C@]2([H])C1)c34)-c1nc(N)cc(C)c1C(F)(F)F

InChI Key InChIKey=ZBVLDYYQJIWNAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619536   

TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50619536(CHEMBL5429318)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed