BDBM50619551 CHEMBL5429450

SMILES [H][C@@]12CN(CCN1c1nc(OC[C@@H]3CCCN3C)nc3cc(c(Cl)c(OC2)c13)-c1nc(N)cc(C)c1C(F)(F)F)C(=O)\C=C\c1nccc2CCNCc12

InChI Key InChIKey=PVQAIVIYDRSCSX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619551   

TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50619551(CHEMBL5429450)
Affinity DataIC50: 180nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed