BDBM50619557 CHEMBL5397857

SMILES CNCc1ccnc(\C=C\C(=O)N2CCN([C@@H](C)C2)c2nc(OC[C@@]34CCCN3CC(=C)C4)nc3c(F)c(c(Cl)cc23)-c2nc(N)cc(C)c2C(F)(F)F)c1

InChI Key InChIKey=XKXGIHHWCKZAFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619557   

TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50619557(CHEMBL5397857)
Affinity DataIC50: 530nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed