BDBM50619558 CHEMBL5406019

SMILES C[C@H]1CN(CCN1c1nc(OC[C@@]23CCCN2CC(=C)C3)nc2c(F)c(c(Cl)cc12)-c1nc(N)cc(C)c1C(F)(F)F)C(=O)\C=C\c1cc(CN2CCOCC2)ccn1

InChI Key InChIKey=ZHHVHDFEGIQVKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619558   

TargetGTPase KRas(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50619558(CHEMBL5406019)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Biotinylated KRAS G13D mutant (unknown origin) incubated for 20 mins in presence of BODIPY-GDP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed