BDBM50620678 CHEMBL5436771

SMILES [S-]C(=S)NCc1cccnc1

InChI Key InChIKey=QNRLUURSWJCRAA-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50620678   

TargetReplicase polyprotein 1ab(2019-nCoV)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50620678(CHEMBL5436771)
Affinity DataIC50: 27nMAssay Description:Inhibition of SARS-CoV-2 N-terminal 6His-SUMO-tagged 3CL protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKM-Glu-Edans fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1a(SARS-CoV)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50620678(CHEMBL5436771)
Affinity DataIC50: 165nMAssay Description:Inhibition of SARS-CoV N-terminal 6His-SUMO-tagged 3CL protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKM-Glu-Edans fluorog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50620678(CHEMBL5436771)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of SARS-CoV-2 N-terminal 6His-SUMO-tagged 3CL protease expressed in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKM-Glu-Edans fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50620678(CHEMBL5436771)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human Cathepsin L using HiLyte Fluor488TM as substrate pre-incubated for 60 mins in presence of GSH followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed