BDBM50621299 CHEMBL5434581

SMILES CC1(C)OB(OC1(C)C)C(NC(=O)c1cnn(Cc2ccc(Cn3cccn3)cc2)c1)c1cccc(Cl)c1

InChI Key InChIKey=UCWICSYWXORFBE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621299   

TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621299(CHEMBL5434581)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 60 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621299(CHEMBL5434581)
Affinity DataIC50: 46nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621299(CHEMBL5434581)
Affinity DataIC50: 255nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 1 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed