BDBM50621836 CHEMBL5423711

SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1Cc2c([nH]c3ccccc23)CNC1=O

InChI Key InChIKey=YKAWDEHFCQNJSK-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50621836   

TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataIC50: 34nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataEC50:  165nMAssay Description:Agonist activity at human MC5R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataIC50: 165nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataIC50: 166nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataEC50:  171nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621836BDBM50621836(CHEMBL5423711)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed