BDBM50621837 CHEMBL5395890

SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccc(C(F)(F)F)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1Cc2c([nH]c3ccccc23)CNC1=O

InChI Key InChIKey=WTTWGJPVLDQEOW-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50621837   

TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC4R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 4(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human MC4R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataIC50: 40nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataIC50: 81nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621837BDBM50621837(CHEMBL5395890)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC3R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed