BDBM50621940 CHEMBL5436545

SMILES CCS(=O)(=O)n1cc(-c2ccnc(Nc3cc(NC(=O)C=C(C)C)c4c(cnn4CCN(C)C)c3)n2)c2ccccc21

InChI Key InChIKey=TYPQOGNWOBATAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621940   

TargetEpidermal growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621940BDBM50621940(CHEMBL5436545)
Affinity DataIC50: 29nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed