BDBM50622011 CHEMBL5405887

SMILES CC(C)C1=NN(C(=O)C1Cc1cc(c[nH]1)C(=O)c1ccccc1[N+]([O-])=O)c1ccc(cc1)C(O)=O

InChI Key InChIKey=MPPGNUPHQUKJHF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622011   

TargetHistone acetyltransferase p300(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50622011(CHEMBL5405887)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant human KAT3B (1287 to 1673 residues) using histone H3 peptide and [3H]-acetyl-coA as substrates incubated for 1 hrs by liqui...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone acetyltransferase KAT8(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50622011(CHEMBL5405887)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of N-terminal 6His tagged KAT8 (173 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using biotinylated histone H...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed