BDBM50622333 CHEMBL5426493

SMILES CN(C)CCNC(=O)Nc1ccc(cc1)-c1ccc2ncn(-c3ccc(Cl)cc3)c2c1

InChI Key InChIKey=IATLKOJNAMYASM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622333   

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622333BDBM50622333(CHEMBL5426493 | US20260015328, Compound FM-987)
Affinity DataIC50: 1nMAssay Description:Inhibition of human ATM kinase using p53 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622333BDBM50622333(CHEMBL5426493 | US20260015328, Compound FM-987)
Affinity DataIC50: 1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent