BDBM50622367 CHEMBL5427404

SMILES COc1cc(cc(OC)c1OC)-c1ccc(cc1)-n1cnc2ccc(cc12)-c1ccc(NC(=O)NCCN(C)C)cc1

InChI Key InChIKey=XVRAIAAWMIFLAL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622367   

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622367BDBM50622367(CHEMBL5427404 | US20260015328, Compound TD-665)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human ATM kinase using p53 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622367BDBM50622367(CHEMBL5427404 | US20260015328, Compound TD-665)
Affinity DataIC50: 4.40nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent