BDBM50622401 CHEMBL5404392

SMILES CN(C)CCCOc1ccc(cn1)-c1ccc2ncn(-c3ccc4CCN(c4c3)S(C)(=O)=O)c2c1

InChI Key InChIKey=RFBKNCGADRVFFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622401   

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of TuBingen

US Patent
LigandChemical structure of BindingDB Monomer ID 50622401BDBM50622401(CHEMBL5404392 | US20260015328, Compound TD-560)
Affinity DataIC50: 2.5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of TuBingen

US Patent
LigandChemical structure of BindingDB Monomer ID 50622401BDBM50622401(CHEMBL5404392 | US20260015328, Compound TD-560)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ATM kinase using p53 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of TuBingen

US Patent
LigandChemical structure of BindingDB Monomer ID 50622401BDBM50622401(CHEMBL5404392 | US20260015328, Compound TD-560)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of ATM kinase in human A549 cells in presence of etoposide by ICW assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed