BDBM50622415 CHEMBL5417382

SMILES CS(=O)(=O)N1CCCc2ccc(cc12)-n1cnc2ccc(nc12)-c1ccc(OCCCN2CCCC2)nc1

InChI Key InChIKey=BGLQAFAEKNCHGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622415   

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622415BDBM50622415(CHEMBL5417382 | US20260015328, Compound TD-684)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human ATM kinase using p53 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622415BDBM50622415(CHEMBL5417382 | US20260015328, Compound TD-684)
Affinity DataIC50: 0.850nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent

TargetSerine-protein kinase ATM(Human)
Eberhard Karls University of Tubingen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622415BDBM50622415(CHEMBL5417382 | US20260015328, Compound TD-684)
Affinity DataIC50: 1nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/28/2026
Entry Details US Patent