BDBM50622495 CHEMBL5417169

SMILES Cc1cc(cc(c1OC(C)(C)C(=O)O)C)CN2C(=O)CN(C2=O)c3ccc(cc3)C(F)(F)F

InChI Key InChIKey=BIIFAYFKMQRXPQ-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622495   

TargetPeroxisome proliferator-activated receptor delta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622495(CHEMBL5417169)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human PPARdelta transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622495(CHEMBL5417169)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human PPARalpha transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622495(CHEMBL5417169)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at human PPARgamma transfected in african green monkey COS7 cells assessed transactivation incubated for 16 hrs by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed