BDBM50622529 CHEMBL5419377

SMILES OC(=O)c1ccc(s1)-c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=BRNQGIMGJSDTMI-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622529   

TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50622529(CHEMBL5419377)
Affinity DataEC50:  40nMAssay Description:Agonist activity at full length human Nurr1 transfected in HEK293T cells co-transfected with pFR-Luc-NRBE assessed as luciferase activity incubated f...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50622529(CHEMBL5419377)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human Nurr1 transfected in HEK293T cells co-transfected with pFR-Luc/pRL-SV40/pFA-CMV-hNurr1-LBD assessed as luciferase activity ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50622529(CHEMBL5419377)
Affinity DataKd:  140nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human Nurr1 LBD (362 to 598 residues) expressed in Escherichia coli BL21(DE3)-R3-pRARE2 by ITC...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed