BDBM50622895 CHEMBL5396476

SMILES [H][C@@]12O[C@]1([C@H](C)[C@@]1([H])CC(CO)=C(C)C(=O)O1)[C@@]1(C)CCC3C(C[C@@H](O)[C@@]4(O)CC=CC(=O)[C@]34C)[C@@]1(O)[C@H]2OC(C)=O

InChI Key InChIKey=VNEYTLXAFWQLRK-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622895   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622895(CHEMBL5396476)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to GLUT1 (unknown origin) assessed as dissociation constant at 800 uM by MST assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622895(CHEMBL5396476)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of GLUT1 in human MCF7 cells assessed as ATP production incubated for 24 hrs in presence of 0.1 mM glucoseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50622895(CHEMBL5396476)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of GLUT1 in human MCF7 cells assessed as ATP production incubated for 24 hrs in presence of 10 mM glucoseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed