BDBM50622915 CHEMBL5415380

SMILES CCNC(=O)c1c(OC)cc(cc1OC(F)F)-n1cnc2cc(ccc12)-c1cnn(C)c1

InChI Key InChIKey=ARXQRVVEKOEUEV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622915   

TargetSerine/threonine-protein kinase SIK3(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50622915(CHEMBL5415380)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SIK3 isoform 1 (59 to 1321 residues) expressed in Sf9 insect cells using AMARA peptide as substrate incubated for 120 mins in pre...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50622915(CHEMBL5415380)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of SIK2 (unknown origin) using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50622915(CHEMBL5415380)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of SIK1 (unknown origin) using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed