BDBM50623120 CHEMBL5434324

SMILES CONC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)c(=O)n(-c3cccc(OC(F)F)c3F)c(=O)c2c1CN(C)C

InChI Key InChIKey=VWZVEJMYVCEEJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623120   

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623120(CHEMBL5434324 | US20250000864, Compound 3)
Affinity DataIC50: 0.260nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shandong Luye Pharmaceutical

US Patent
LigandPNGBDBM50623120(CHEMBL5434324 | US20250000864, Compound 3)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [1251][D-Trp6]-LH-RH from human GnRH-R expressed in Chem-1 cells incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed