BDBM50623129 CHEMBL5419365

SMILES COc1ccc(nn1)-n1c(=O)n(Cc2c(F)cccc2F)c2sc(c(CN(C)C)c2c1=O)-c1ccc(NC(=O)NOCC(F)F)cc1

InChI Key InChIKey=JBJOXDPVMGPNDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623129   

TargetGonadotropin-releasing hormone receptor(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50623129(CHEMBL5419365 | US20250000864, Compound 7)
Affinity DataIC50: 0.220nMAssay Description:Displacement of [1251][D-Trp6]-LH-RH from human GnRH-R expressed in Chem-1 cells incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM50623129(CHEMBL5419365 | US20250000864, Compound 7)
Affinity DataIC50: 0.220nMAssay Description:Equipment: MicroBeta2 LumiJET system, PerkinElmer. Method: Chem-1 cell membranes stably expressing human GnRHR were resuspended in HEPES at pH 7.4. 6...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
5/15/2025
Entry Details
US Patent