BDBM50623278 CHEMBL5408150

SMILES Cc1[nH]c(C(=O)Nc2ccc(cc2OCc2ccc(cc2)C(=O)NCCN)C(N)=O)c(Cl)c1Cl

InChI Key InChIKey=DXFOJQSWALTPJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50623278   

TargetDNA topoisomerase 2-beta(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623278(CHEMBL5408150)
Affinity DataIC50: 550nMAssay Description:Inhibition of human DNA topoisomerase 2 beta assessed as relaxation of supercoiled plasmid pBR322 DNA incubated for 30 mins by ethidium bromide stain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623278(CHEMBL5408150)
Affinity DataIC50: 670nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50623278(CHEMBL5408150)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DNA Topoisomerase 1 assessed as relaxation of supercoiled plasmid pBR322 DNA incubated for 30 mins by ethidium bromide staining b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed