BDBM50623351 CHEMBL5408703

SMILES CO[C@](C(=O)Nc1c2CSCc2nn1-c1ccc(Br)cc1)(c1ccccc1)C(F)(F)F

InChI Key InChIKey=YYGCENQZOBNUEI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623351   

TargetAutotaxin(Human)
Bioinnovation Institute

Curated by ChEMBL
LigandPNGBDBM50623351(CHEMBL5408703)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ATX using LPC as substrate preincubated with compound for 15 mins followed by substrate addition measured after 30 mins by Amplex...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Bioinnovation Institute

Curated by ChEMBL
LigandPNGBDBM50623351(CHEMBL5408703)
Affinity DataKi:  6.83E+3nMAssay Description:Mixed type inhibition of human ATX assessed as inhibition constant using LPC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed