BDBM50624017 CHEMBL5438441

SMILES OC(=O)C1(CC1)c1ccc(c(F)c1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=DFJGLZRYGZSQOR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50624017   

TargetAldo-keto reductase family 1 member C3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant AKR1C3 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of human recombinant AKR1C1 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1B1 (unknown origin) transfected in Escherichia coli BL21 (DE3) pLysS competent cells using pyridine-3-aldehyde as substrate assesse...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AKR1C4 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624017(CHEMBL5438441)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKR1B10 (unknown origin) transfected in Escherichia coli BL21 (DE3) pLysS competent cells using pyridine-3-aldehyde as substrate assess...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed