BDBM50624105 CHEMBL5408308

SMILES Cc1ccc(CNC(=O)c2cc(\C=C\C(O)=O)cc(c2)-c2ccc3cccnc3c2)cc1

InChI Key InChIKey=LCBJGOZMBFXQSG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50624105   

TargetAldo-keto reductase family 1 member C3(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 110nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/17/2026
Entry Details ArticleUS Patent

TargetAldo-keto reductase family 1 member C2(Human)
University of Nebraska

US Patent
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 1.20E+4nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/17/2026
Entry Details ArticleUS Patent

TargetAldo-keto reductase family 1 member C2(Human)
University of Nebraska

US Patent
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant AKR1C4 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 2.20E+4nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/17/2026
Entry Details ArticleUS Patent

TargetAldo-keto reductase family 1 member C1(Human)
University of Nebraska

US Patent
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 8.00E+4nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/17/2026
Entry Details ArticleUS Patent

TargetAldo-keto reductase family 1 member C1(Human)
University of Nebraska

US Patent
LigandChemical structure of BindingDB Monomer ID 50624105BDBM50624105(CHEMBL5408308 | US20260035340, Compound A1-p)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of recombinant AKR1C1 (unknown origin) dehydrogenase activity by measuring NADH formation by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed