BDBM50624231 CHEMBL5422297

SMILES COc1cc(cc(OC)c1F)N(C(=O)CCl)c1ccc2OCCOc2c1

InChI Key InChIKey=HKXSBJJCHBFTMB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624231   

TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624231(CHEMBL5422297)
Affinity DataIC50: 120nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624231(CHEMBL5422297)
Affinity DataKi:  630nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed