BDBM50624329 CHEMBL5413976

SMILES COc1cccc(Cn2c3cccc4c3c(cc3cccnc23)n(C)c4=O)c1

InChI Key InChIKey=DTEGBGJOVGYCCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624329   

TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624329(CHEMBL5413976)
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD2 (44 to 460 residues) expressed in Escherichia coli using biotinylated H4K5acK8acK12acK...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624329(CHEMBL5413976)
Affinity DataIC50: 685nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD1 (44 to 460 residues) expressed in Escherichia coli using biotinylated H4K5acK8acK12acK...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed