BDBM50624343 CHEMBL5393744

SMILES CN1CCC(CC1)NC(=O)c1cccc(Cn2c3cccc4c3c(cc3ccccc23)n(C)c4=O)c1

InChI Key InChIKey=GVCFSBGCJBRHFS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50624343   

TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD2 (44 to 460 residues) expressed in Escherichia coli using biotinylated H4K5acK8acK12acK...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD2 (44 to 460 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD2 BD2 (2 to 473 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD3 BD2 (1 to 434 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 465nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD3 BD1 (1 to 434 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 524nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD1 (44 to 460 residues) expressed in Escherichia coli using biotinylated H4K5acK8acK12acK...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 524nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD4 BD1 (44 to 460 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 527nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRDT BD1 (21 to 383 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624343(CHEMBL5393744)
Affinity DataIC50: 570nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BRD2 BD1 (2 to 473 residues) expressed in Escherichia coli by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed