BDBM50624415 CHEMBL5403355

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2nc(-c3ccccc3)n(n2)-c2cccc(Cl)c2)cc1

InChI Key InChIKey=LAKUGUCGXZVQEE-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50624415   

TargetCarbonic anhydrase 7(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624415(CHEMBL5403355)
Affinity DataKi:  8.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624415(CHEMBL5403355)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624415(CHEMBL5403355)
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624415(CHEMBL5403355)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR-2 (unknown origin) incubated for 45 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Kafrelsheikh University

Curated by ChEMBL
LigandPNGBDBM50624415(CHEMBL5403355)
Affinity DataKi:  2.69E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by phenol red based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed