BDBM50625100 CHEMBL5408197

SMILES Oc1ccc(\C=C2/Cc3c(cccc3O)C2=O)c(O)c1

InChI Key InChIKey=JXTXSXXNWUNVNR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50625100   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataIC50: 90nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by absorba...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataKi:  250nMAssay Description:Binding affinity to His-tagged human tyrosinase expressed in HEK293 cells assessed as inhibition constant by HTS assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataKi:  250nMAssay Description:Inhibition of C-terminal His-tagged truncated form of human tyrosinase (1 to 456 residues) expressed in HEK293T cells using L-DOPA as substrate asses...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataKi:  250nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50625100(CHEMBL5408197)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed