BDBM50625257 CHEMBL5417858

SMILES Nc1ccccc1NC(=O)c1ccc(NC(=O)Cc2ccc3ccccc3c2)cn1

InChI Key InChIKey=MOHPPFRGEVZIHW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50625257   

TargetHistone deacetylase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625257(CHEMBL5417858)
Affinity DataIC50: 189nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625257(CHEMBL5417858)
Affinity DataIC50: 227nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625257(CHEMBL5417858)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant HDAC3 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50625257(CHEMBL5417858)
Affinity DataIC50: 446nMAssay Description:Inhibition of human recombinant HDAC10 using fluorogenic p53 (379-382 residues) (RHKK(Ac)AMC) as substrateMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed