BDBM50625575 CHEMBL5414905

SMILES CCc1cnn2c(NCc3nc4ccc(F)c(F)c4[nH]3)cc(nc12)N1CCCC[C@H]1CCO

InChI Key InChIKey=UQKMSJFNACXHSL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50625575   

TargetCyclin-dependent kinase 12(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged recombinant human CDK12 (696 to 1082 residues) expressed in Insect cell in presence of ATP by Km ATP assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 40nMAssay Description:Inhibition of full length recombinant human CDK2 expressed in Insect cell in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 47nMAssay Description:Inhibition of GST-tagged recombinant human CDK12 (696 to 1082 residues) expressed in Insect cell in presence of ATP by high ATP assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 240nMAssay Description:Inhibition of full length recombinant human CDK9 expressed in Insect cell in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of full length recombinant human CDK1 expressed in Insect cell in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50625575(CHEMBL5414905)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of full length recombinant human CDK7 expressed in Insect cell in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed