BDBM50625844 CHEMBL5422204

SMILES CCCCCc1nnc(NC(=S)NS(=O)(=O)c2ccc(C)cc2)s1

InChI Key InChIKey=MGLVZTMWFGPIGD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50625844   

TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 230nMAssay Description:Inhibition of Staphylococcus aureus dihydrofolate reductase using dihydrofolate as substrate in presence of NADPH by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDNA topoisomerase 4 subunit B(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50625844(CHEMBL5422204)
Affinity DataIC50: 5.38E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 subunit B ATPase activity using relaxed pNO1 plasmid as substrate incubated for 30 mins by mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed