BDBM50625865 CHEMBL5394881

SMILES CN1CCN(C(=O)c2cnc(Nc3c4CCCc4cc4CCCc34)o2)S1(=O)=O

InChI Key InChIKey=STNSOELAKWNRNX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50625865   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50625865(CHEMBL5394881)
Affinity DataIC50: 300nMAssay Description:Inhibition of NLRP3 in LPS/nigericin-induced human THP-1 cells assessed as inhibition of IL-1beta production pretreated with LPS for 3 hrs followed b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed