BDBM50626359 CHEMBL5435156

SMILES CC(C)Nc1ccc(c(Nc2ccc3n(nnc3c2)S(=O)(=O)c2ccc(F)cc2)n1)[N+]([O-])=O

InChI Key InChIKey=ORQHVURKSCPKMT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626359   

TargetBromodomain-containing protein 4(Human)
University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50626359(CHEMBL5435156)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal 6His-tagged BRD4 BD1 (47 to 170 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50626359(CHEMBL5435156)
Affinity DataIC50: 6.17E+3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using SGRGK(Ac)GGK(Ac)GLGK(Ac) GGAK(Ac)RHRK-biotinylated peptide as substrate incubated for 60 mins by alpha ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed