BDBM50626855 CHEMBL5401788

SMILES C[C@H](N1C(=O)C2CCCCC2C1=O)C(=O)N1[C@@H](C)C[C@@H](Nc2ccccc2)c2ccccc12

InChI Key InChIKey=PSCGFZKDBAPWLN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50626855   

TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626855(CHEMBL5401788)
Affinity DataEC50:  980nMAssay Description:Agonist activity at Gal4-fused FXR LBD (unknown origin) transfected in HEK293T cells co-transfected with Peak12-Gal4UAS-luci assessed as receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Chinese Academy of Medical Sciences&Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50626855(CHEMBL5401788)
Affinity DataEC50:  3.30E+3nMAssay Description:Agonist activity at FXR (unknown origin) assessed as SRC2 recruitment by LanthaScreen TR-FRET FXR coactivator assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed