BDBM50627738 CHEMBL5407378

SMILES OC(=O)c1cc(C(O)=O)c(NCc2ccc(cc2)C(F)(F)F)cn1

InChI Key InChIKey=JLTOQVPSWXCZNO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50627738   

TargetBifunctional peptidase and arginyl-hydroxylase JMJD5(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50627738(CHEMBL5407378)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal his6-tagged-thioredoxin-tagged human recombinant JMJD5 expressed in Escherichia coli using RPS6 as substrate by SPE-MS analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetAspartyl/asparaginyl beta-hydroxylase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50627738(CHEMBL5407378)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal his6-tagged AspH (315 to 758 residues) (unknown origin) expressed in Escherichia coli by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50627738(CHEMBL5407378)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of N-terminal his6-tagged human recombinant KDM4E expressed in Escherichia coli using K9me3 as substrate by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetRibosomal oxygenase 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50627738(CHEMBL5407378)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of N-terminal his6-tagged RIOX2 (26 to 465 residues) (unknown origin) expressed in Escherichia coli using RPL27A (31 to 49 residues) as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50627738(CHEMBL5407378)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PHD2 (181 to 426 residues) (unknown origin) expressed in Escherichia coli using HIF-alpha- CODD 558 to 574 residues) by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed