BDBM50628376 CHEMBL5416354

SMILES COc1cc(Nc2nc(NCc3ccc(Cl)c(NC(=O)C=C)c3)n3ccnc3c2C(N)=O)ccc1N1CCN(C)CC1

InChI Key InChIKey=AYZVUGQJVYMELX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50628376   

TargetTyrosine-protein kinase ZAP-70(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628376(CHEMBL5416354)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of ZAP-70 (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase SYK(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50628376(CHEMBL5416354)
Affinity DataIC50: 532nMAssay Description:Inhibition of SYK (unknown origin) using ULight-TK peptide as substrate incubated for 120 mins in presence of ATP by Lance Ultra Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed